Musculoskeletal

As far as imaging can see

The number and types of analyses that can be performed in musculoskeletal imaging is limitless. At Imaging Endpoints, we can measure virtually anything, but care must be taken to ensure that incoming imaging is the right quality and data extracted is meaningful.

Small variations in measurements can lead to huge variances in outcomes, which is why musculoskeletal analyses must be performed by radiologists with superior training in anatomy and pathology. No technician or technology has the sophistication, experience, and knowledge base to supplant a radiologist's eye when your clinical trial data is at stake. Imaging Endpoints is owned and operated by radiologists, thereby giving you an expert advantage in your clinical development programs.

The therapeutic areas that MSK encompasses are extremely diverse, and the optimal imaging strategies vary just as broadly. To ensure consistency and reliability of results, Imaging Endpoints strongly recommends building imaging into your project plan as a core component.

The musculoskeletal radiology team at Imaging Endpoints consists of board-certified, specialty-trained radiologists with broad experience in musculoskeletal imaging, including trauma and related hardware, podiatry (foot and ankle), 3D reconstruction, and total joint replacements.

Imaging study expertise includes, but is not limited to, the following trial areas: 

Trauma
Orthopedic devices-various
Rheumatoid arthritis
Osteoarthritis

Muscle wasting diseases
Spinal interventions
(kyphoplasty, vertebroplasty)
Spinal fusion surgeries

Assessments  

Quantitative

  • BMD through QCT, DXA, clinical CT (without the use of an external phantom)
  • Vertebral and disc measurements (volume, height, etc.)
  • Bone age
  • Bone and Muscle volumes
  • Intramuscular and subcutaneous fat volume
  • Total enhancing tissue in RA

Semi-quantitative

  • Bone graft incorporation

 

Qualitative

  • Fracture characterization and healing assessments
  • Spinal fusion success
  • Disc degeneration
  • Enhancing synovium in RA
  • Bone marrow edema in RA
  • Cartilage and bone morphology

 

Modalities
 
  • CT-qCT
  • MRI
  • X-Ray
  • DEXA
  • PET/CT