SCOTTSDALE, Ariz., Sept. 12, 2019, /PRNewswire/ -- Imaging Endpoints (IE) has announced the opening of its new corporate headquarters in Scottsdale, Arizona to accommodate the company's tremendous growth. The company also has an office in Waltham, Massachusetts as well as… Read More
Summary Malignant melanoma (MM) exhibits a high propensity for central nervous system dissemination with ~50% of metastatic MM patients developing brain metastases (BM). Targeted therapies and immune checkpoint inhibitors have improved overall survival for MM patients with BM. However, responses… Read More
Archival tumor samples represent a rich resource of annotated specimens for translational genomics research. However, standard variant calling approaches require a matched normal sample from the same individual, which is often not available in the retrospective setting, making it difficult… Read More
Abstract Pancreas cancer is an aggressive and fatal disease that will become one of the leading causes of cancer mortality by 2030. An all-out effort is underway to better understand the basic biologic mechanisms of this disease ranging from early… Read More
Abstract Background. Molecular analysis has revealed four subtypes of pancreatic ductal adenocarcinoma (PDAC). One subtype identified for the presence of DNA damage repair deficiency can be targeted therapeutically with the poly (ADP‐ribose) polymerase (PARP) inhibitor olaparib. We performed a single-institution… Read More
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