Epigenetic alterations have been strongly associated with tumour formation and resistance to chemotherapeutic drugs, and epigenetic modifications are an attractive target in cancer research. RRx-001 is activated by hypoxia and induces the generation of reactive oxygen and nitrogen species that… Read More
Abstract Background: For patients with metastatic pancreatic adenocarcinoma, there are no approved or established treatments beyond the 2nd line. A Phase Ib study of fractionated radioimmunotherapy was undertaken in this setting, administering 90Y-clivatuzumab tetraxetan (yttrium-90-radiolabelled humanised antibody targeting pancreatic adenocarcinoma… Read More
Radiogenomics should be an integral part of drug development, according to Dr Korn who talks to ecancer about this evolving field at TAT 2015.
April 2014 - Ron Korn, MD, PhD, of Imaging Endpoints will be a featured presenter at Pharmatech's Biomarker Panel entitled "Development of Oncology Clinical Trials in the time of Precision, Personalized Medicine" occurring on May 15, 2014 at the Marriott… Read More
Purpose: To present a radiogenomic computed tomographic (CT) characterization of anaplastic lymphoma kinase (ALK) rearranged non–small cell lung cancer (NSCLC) (ALK+). Materials and Methods: In this HIPAA-compliant institutional review board–approved retrospective study, CT studies, ALK status, and clinical-pathologic data in… Read More
Abstract Background: Non-invasive characterization of a tumor’s molecular features could enhance treatment management. Quantitative computed tomography (CT) based texture analysis (QTA) has been used to derive tumor heterogeneity information, and the appearance of the tumors has been shown to relate… Read More
Boston, MA – May 7, 2014 – AG Mednet and the board-certified, fellowship-trained radiologists at Imaging Endpoints believe strongly that every clinical trial data point counts, from pre-clinical through FDA submission. To support its guarantee of accuracy, compliance, real-time reads… Read More
April 2014 - Imaging Endpoints presents Poster at AACR 2014 in conjunction with Merrimack Pharmaceuticals and Virginia C. Piper Cancer Center. The Poster, entitled "Pilot study in patients with advanced solid tumors to evaluate feasibility of ferumoxytol (FMX) as a… Read More
April 2014 - Imaging Endpoints presents Poster at AACR 2014 in conjunction with RadioRx, Inc. and the University Of Arizona College Of Medicine. The Poster, entitled "RRx-001 Oxidation of Redox Sensitive Protein Thiols in Tumors Measured by Gd-LC7-SH Enhanced MRI… Read More
April 2014 - Imaging Endpoints presents Poster at AACR 2014 in conjunction with the University Of Arizona College Of Medicine, The Translational Genomics Research Institute (TGen) and The Virginia G. Piper Cancer Center. The Poster, entitled "Quantitative Textural Analysis (QTA)… Read More
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Radiologic Analysis of COVID-19 Infection
June 23, 2020
