Pancreatic cancer could it be that simple? A different context of vulnerability.
In a recent issue of Science, Olive and colleagues document that inhibition of Hedgehog (Hh) signaling in a genetically engineered mouse model of pancreatic cancer can enhance the intratumor concentration of certain anticancer drugs. Could this finding provide us with a new method to attack pancreatic cancer?
Von Hoff D.D., Korn R. and Mousses S. “Pancreatic cancer–could it be that simple? A different context of vulnerability.” Cancer Cell, 16(1): 7-8, (2009).